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E-AB-81467

Recombinant Estrogen Receptor alpha Monoclonal Antibody

Size

£178.20

Was £198.00

SKU:
E-AB-81467
Additional Names:
4,5,6,7*,7*/822 isoform,8*/941 isof,DKFZp686N23123,ER,ER alpha,ER-alpha,ESR,ESR1,ESRA,Era,Estradiol receptor,Estrogen nuclear receptor alpha,Estrogen receptor 1,Estrogen receptor alpha,Estrogen receptor alpha 3*,Estrogen receptor alpha delta 3*
Application:
IHC, WB, IHC-P, IF
Concentration:
300 ug/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:
A synthetic peptide of human Estrogen Receptor alpha
Clone:
R05-1E4
Uniprot:
P03372
Synonyms:
E2 receptor alpha;ER;ER-alpha;Era;ESR;ESRA;estradiol receptor;estrogen nuclear receptor alpha;estrogen receptor;estrogen receptor alpha E1-E2-1-2;estrogen receptor alpha E1-N2-E2-1-2;ESTRR;NR3A1;nuclear receptor subfamily 3 group A member 1;oestrogen receptor alpha
Extra Details:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Shipping Conditions:
Blue Ice