E-AB-81443
Recombinant c Myc Monoclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-81443
- Additional Names:
- AU016757,Avian myelocytomatosis viral oncogene homolog,Class E basic helix-loop-helix protein 39,MRTL,MYC,MYCC,Myc,Myc protein,Myc proto oncogene protein,Myc proto-oncogene protein,Myc2,bHLHe39,c Myc,myc-related translation/localization regulatory factor
- Application:
- WB
- Concentration:
- 300 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- A synthetic peptide of human c-Myc
- Clone:
- R05-5E2
- Uniprot:
- P01106
- Synonyms:
- avian myelocytomatosis viral oncogene homolog;bHLHe39;c-Myc;class E basic helix-loop-helix protein 39;MRTL;myc proto-oncogene protein;myc-related translation/localization regulatory factor;MYCC;proto-oncogene c-Myc;transcription factor p64;v-myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog
- Extra Details:
- This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
- Shipping Conditions:
- Blue Ice