E-AB-81439
Recombinant EGFR Monoclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-81439
- Additional Names:
- Cell growth inhibiting protein 40,Cell proliferation inducing protein 61,E,EGF R,EGFR,ERBB,Epidermal growth factor receptor,Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog),erb-b2 receptor tyrosine kinase 1
- Application:
- WB, IF
- Concentration:
- 300 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- A synthetic peptide of human EGFR
- Clone:
- R03-6B1
- Uniprot:
- P00533
- Synonyms:
- avian erythroblastic leukemia viral (v-erb-b) oncogene homolog;cell growth inhibiting protein 40;cell proliferation-inducing protein 61;epidermal growth factor receptor;epidermal growth factor receptor tyrosine kinase domain;erb-b2 receptor tyrosine kinase 1;ERBB;ERBB1;ERRP;HER1;mENA;NISBD2;PIG61;proto-oncogene c-ErbB-1;receptor tyrosine-protein kinase erbB-1
- Extra Details:
- EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.
- Shipping Conditions:
- Blue Ice