E-AB-70381
PI 3 kinase p85 alpha Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70381
- Additional Names:
- GRB1,P85A,Phosphatidylinositol 3 kinase,Phosphatidylinositol 3 kinase associated p 85 alpha,Phosphatidylinositol 3 kinase regulatory 1,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,p85,p85 alpha,polypeptide 1 (p85 alpha),regulatory subunit
- Application:
- WB
- Concentration:
- 1.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant protein corresponding to Human PI 3 Kinase p85 alpha.
- Uniprot:
- P26450, P27986, Q63787
- Synonyms:
- AGM7;GRB1;IMD36;p50;p50alpha;p55;p55alpha;p85;p85-ALPHA;p85alpha;phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;phosphatidylinositol 3-kinase p85 alpha;phosphatidylinositol 3-kinase regulatory subunit alpha;phosphatidylinositol 3-kinase-associated p-85 alpha;phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha);Phosphoinositide 3-kinase p85 (other splicing variants: p55 and p50);Phosphoinositide 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha);phosphoinositide-3-kinase regulatory subunit alpha;phosphoinositide-3-kinase, regulatory subunit 1 (alpha);PI;PI3-kinase p85 subunit alpha;PI3-kinase regulatory subunit alpha;PI3-kinase subunit p85-alpha;PI3K;PI3K regulatory subunit alpha;PI3KA;ptdIns-3-kinase p85-alpha;ptdIns-3-kinase regulatory subunit alpha;ptdIns-3-kinase regulatory subunit p85-alpha
- Extra Details:
- Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer,which is composed of a P110 catalytic subunit and a P85 regulatory subunit,is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
- Shipping Conditions:
- Blue Ice