E-AB-70361
CCR5 Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70361
- Additional Names:
- AM4 7,C C CKR 5,C C chemokine receptor type 5,C-C CKR-5,C-C chemokine receptor type 5,C-C motif chemokine receptor 5 A159A,CC CKR 5,CC Chemokine Receptor 5,CC Chemokine Receptor Type 5,CC-CKR-5,CCCKR 5,CCCKR5,CCR 5,CCR-5,CCR5,CCR5 chemokine (C C motif) re
- Application:
- IHC
- Concentration:
- 0.55 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse CCR5
- Uniprot:
- O08556, P51682
- Synonyms:
- AM4-7;C-C chemokine receptor type 5;C-C CKR-5;CC-CKR-5;CCR-5;CD195;chemokine (C-C motif) receptor 5;chemokine (C-C) receptor 5;Ckr5;Cmkbr;Cmkbr5;MIP-1 alpha receptor
- Extra Details:
- This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.
- Shipping Conditions:
- Blue Ice