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E-AB-70353

AIF1 Monoclonal Antibody

Size

£178.20

Was £198.00

SKU:
E-AB-70353
Additional Names:
AIF 1,AIF-1,AIF1,AIF1 protein,Aif1,Allograft inflammatory factor 1,Allograft inflammatory factor 1 splice variant G,BART 1,G1,G1 putative splice variant of ,allograft inflammatory factor-1 splice variant Hara-1,balloon angioplasty responsive transcription
Application:
IHC
Concentration:
1.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Mouse
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
Recombinant protein corresponding to Mouse IBA-1
Clone:
5G4E7
Uniprot:
O70200
Synonyms:
AI607846;AIF-1;allograft inflammatory factor 1;D17H6S50;D17H6S50E;G1;Ib;Iba1;ionized calcium binding adapter molecule 1;Ionized calcium-binding adapter molecule 1;testis specific
Extra Details:
This gene is induced by cytokines and interferon.Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma.Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation.Enhances the actin-bundling activity of LCP1.Binds calcium.Plays a role in RAC signaling and in phagocytosis.May play a role in macrophage activation and function.Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.Enhances lymphocyte migration.Plays a role in vascular inflammation.
Shipping Conditions:
Blue Ice