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E-AB-70351

p19 INK4d Polyclonal Antibody

Size

£178.20

Was £198.00

SKU:
E-AB-70351
Additional Names:
inhibits CDK4),CDK inhibitor p19INK4d,CDKN2D,Cyclin dependent kinase inhibitor 2D,Cyclin-dependent kinase 4 inhibitor D,Cyclin-dependent kinase inhibitor 2D (p19,INK4D,MGC109660,MGC137547,MGC73010,inhibitor of cyclin-dependent kinase 4d,p19,p19-INK4D
Application:
WB
Concentration:
2.6 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse p19 INK4d
Uniprot:
P55273, Q60773
Synonyms:
CDK inhibitor p19INK4d;cell cycle inhibitor, Nur77 associating protein;cyclin-dependent kinase 4 inhibitor D;cyclin-dependent kinase 4 inhibitor D p19;cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4);inhibitor of cyclin-dependent kinase 4d;INK;INK4D;p1;p19;p19-INK4D;p19IN;p19INK4d
Extra Details:
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
Shipping Conditions:
Blue Ice