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E-AB-70306

CD163 Polyclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-70306
Additional Names:
C163A,CD 163,CD163,CD163 antigen,CD163 molecule,Hemoglobin scavenger receptor,M130,M130 antigen precursor,MM130,Macrophage associated antigen,OTTHUMP00000238617,OTTHUMP00000238618,OTTHUMP00000238619,OTTHUMP00000238620,SCARI1,Scavenger receptor cysteine ri
Application:
WB
Concentration:
360 ug/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
Recombinant protein corresponding to Mouse CD163
Uniprot:
Q2VLH6, Q86VB7
Synonyms:
CD163v2;CD163v3;hemoglobin scavenger receptor;M130;macrophage-associated antigen;MM130;SCARI1;scavenger receptor cysteine-rich type 1 protein M130
Extra Details:
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Shipping Conditions:
Blue Ice