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E-AB-70276

AGT Polyclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-70276
Additional Names:
A,AGT,AI265500,ANGT,ANHU,ANRT,Aangiotensinogen (serpin peptidase inhibitor clade A member 8),Alpha 1 antiproteinase antitrypsin,Ang,Ang I,Ang II,Ang III,AngII,Angiotensin I,Angiotensin II,Angiotensin III,Angiotensin-3,Angiotensinogen,Angiotensinogen (PAT)
Application:
WB
Concentration:
1.7 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Angiotensinogen
Uniprot:
P01015, P11859
Synonyms:
Ang;AngII;angiotensin II;angiotensinogen;angiotensinogen (serpin peptidase inhibitor, clade A, member 8);ANRT;PAT;serpin A8
Extra Details:
Angiotensinogen is a precursor of angiotensin II (Ang II),is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product,angiotensin I,is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension,and can cause renal tubular dysgenesis,a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation,and inflammatory bowel disease.
Shipping Conditions:
Blue Ice