CYBB Polyclonal Antibody

Size

£178.20

Was £198.00

SKU:: E-AB-70273
Additional Names:: AMCBX2,CGD,CGD91-phox,CY24B,CYBB,Cytochrome b 245,Cytochrome b(558) beta chain,Cytochrome b(558) subunit beta,Cytochrome b-245 heavy chain,Cytochrome b558 subunit beta,GP91 PHOX,GP91PHOX,Heme-binding membrane glycoprotein,beta polypeptide,gp91-1,gp91-phox
Application:: IHC
Concentration:: 270 ug/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:: Recombinant protein corresponding to Mouse NOX2
Uniprot:: Q61093
Synonyms:: C88302;Cgd;CGD91-phox;Cyd;cytochrome b-245 heavy chain;Cytochrome b(558) subunit beta;cytochrome b558 subunit beta;gp91-1;gp91-phox;gp91<ph;gp91p;gp91phox;heme-binding membrane glycoprotein gp91phox;NADPH oxidase 2;neutrophil cytochrome b 91 kDa polypeptide;No;Nox2;p22 phagocyte B-cytochrome
Extra Details:: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain.It has been proposed as a primary component of the microbicidal oxidase system of phagocytes.CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD).In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.