E-AB-70271
BSG Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70271
- Additional Names:
- 5A11 antigen,5F7,BASI,Basigin,Basigin (Ok blood group),Blood brain barrier HT7 antigen,Bsg,CD 147,CD147,CD147 antigen,Collagenase stimulatory factor,EMMPRIN,Extracellular matrix metalloproteinase inducer,Leukocyte activation antigen M6,M 6,M6,M6 leukocyte
- Application:
- IHC
- Concentration:
- 370 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant protein corresponding to Mouse CD147
- Uniprot:
- P18572, P26453, P35613
- Synonyms:
- 5A11;5A11/Basigin;5F7;AI115436;AI325119;basic immunoglobulin superfamily;basigin;Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian);basignin;Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian);CD147;CE9;collagenase stimulatory factor;EMM;EMMPRIN;EMPRIN;extracellular matrix metalloproteinase inducer;glycoprotein CE9;gp 42;HAb18G;hepatoma-associated antigen;HT-7;HT7;HT7 antigen;leukocyte activation antigen M6;membrane glycoprotein gp42;neuro;neurothelin;OK;OK blood group antigen;OX-47 antigen;Ox47R;SLC7A11;TCSF;tumor cell-derived collagenase stimulatory factor
- Extra Details:
- BSG,also named as 5F7,Basigin,EMMPRIN,TCSF and CD147,plays pivotal roles in spermatogenesis,embryo implantation,neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1,SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA,inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix,plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
- Shipping Conditions:
- Blue Ice