E-AB-70249
E-Cadherin Monoclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70249
- Additional Names:
- Arc 1,CADH1,CAM 120/80,CD 324,CD324,CD324 antigen,CDHE,Cadherin 1,Cadherin1,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin,cadherin 1 type 1 E-cadherin,cdh1,epithelial calcium dependant adhesion protein
- Application:
- IHC
- Concentration:
- 1.6 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant protein corresponding to MouseE-cadherin
- Clone:
- EC125D
- Uniprot:
- P09803, Q9R0T4
- Synonyms:
- AA960649;ARC-1;cadherin-1;E-ca;E-cad;E-cadh;E-cadherin;Eca;Ecad;epithelial cadherin;L-C;L-CAM;Um;UVO;uvomorulin
- Extra Details:
- This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
- Shipping Conditions:
- Blue Ice