E-AB-70245
SOCS1 Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70245
- Additional Names:
- CISH 1,CISH1,Cytokine inducible SH2 protein 1,JAB,JAK binding protein,JAK-binding protein,Janus kinase binding protein,SOCS 1,SOCS-1,SOCS1,SSI 1,SSI-1,SSI1,STAT induced STAT inhibitor 1,STAT-induced STAT inhibitor 1,Socs1,Suppressor of cytokine signaling
- Application:
- IHC
- Concentration:
- 0.89 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse SOCS1
- Uniprot:
- O35716, Q9QX78
- Synonyms:
- Cis;Cish1;Cish7;cytokine inducible SH2-containing protein 1;cytokine inducible SH2-containing protein 7;JA;JAB;JAK-binding protein;JAK2-binding protein;SOC;SOCS-1;SS;SSI-1;STAT-induced STAT inhibitor 1;suppressor of cytokine signaling 1
- Extra Details:
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
- Shipping Conditions:
- Blue Ice