E-AB-70237
BRAF Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70237
- Additional Names:
- 94 kDa B raf protein,B RAF1,B Raf proto oncogene,B Raf proto oncogene serine threonine protein kinase,B raf 1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),BRAF,BRAF 1,BRAF1,FLJ95109,MGC126806,MGC138284,Muri,cRmil,serine/threonine kinase
- Application:
- IHC
- Concentration:
- 0.74 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse B-Ra
- Uniprot:
- P28028
- Synonyms:
- 9930012E13Rik;AA120551;AA387315;AA473386;B-raf;B-Raf proto-oncogene serine/threonine-protein kinase (p94);Bra;Braf-2;Braf2;C230098H17;C87398;D6Ertd631;D6Ertd631e;proto-oncogene B-Raf;serine/threonine-protein kinase B-raf
- Extra Details:
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
- Shipping Conditions:
- Blue Ice