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E-AB-70229

CD284 Monoclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-70229
Additional Names:
ARMD10,CD284,CD284 antigen,Homolog of Drosophila toll,TLR 4,TLR4,TOLL,Toll like receptor 4,Toll-like receptor 4,hToll
Application:
IHC
Concentration:
1.8 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Mouse
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
Recombinant protein corresponding to Mouse TLR4
Clone:
2E12C8
Uniprot:
Q9QUK6, Q9QX05
Synonyms:
lipopolysaccharide response;Lps;Ly87;Ran/M1;Ras;Rasl2-8;Toll like receptor 4;toll-like receptor 4;toll4
Extra Details:
TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Shipping Conditions:
Blue Ice