E-AB-70225
ACTN1 Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70225
- Additional Names:
- ACTN 1,ACTN1,Actinin alpha 1,Actn1,Alpha Actinin 1,Alpha actinin cytoskeletal isoform,Alpha-actinin cytoskeletal isoform,Alpha-actinin-1,BDPLT15,F,F actin cross linking protein,F-actin cross-linking protein,FLJ40884,actinin,actinin 1 smooth muscle,alpha 1
- Application:
- WB
- Concentration:
- 0.66 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant protein corresponding to MouseA Alpha-actinin1
- Uniprot:
- P12814, Q7TPR4, Q9Z1P2
- Synonyms:
- 3110023F10Rik;actinin 1 smooth muscle;Actn1a;alpha actinin 1a;Alpha-actinin cytoskeletal isoform;alpha-actinin-1;BDPLT15;epididymis secretory sperm binding protein;F-actin cross-linking protein;non-muscle alpha-actinin-1
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice