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E-AB-70215

NOX4 Polyclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-70215
Additional Names:
KOX,KOX 1,KOX1,Kidney oxidase 1,Kidney oxidase-1,Kidney superoxide producing NADPH oxidase,Kidney superoxide-producing NADPH oxidase,Kox-1,NADPH,NADPH oxidase 4,NOX4,Nox4,RENOX,Renal NAD(P)H oxidase,Renal NAD(P)H-oxidase
Application:
IHC, WB
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse NOX4
Uniprot:
Q924V1, Q9JHI8, Q9NPH5
Synonyms:
AI648021;kidney oxidase-1;kidney superoxide-producing NADPH oxidase;KOX;KOX-1;NADPH oxidase 4;renal NAD(P)H-oxidase;RENOX;superoxide-generating NADPH oxidase 4
Extra Details:
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice