E-AB-70170
LEP Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70170
- Additional Names:
- FLJ94114,LEP,LEPD,Leptin,Leptin (murine obesity homolog),Leptin (obesity homolog,Leptin Murine Obesity Homolog,Leptin Precursor Obesity Factor,OB,Obese,Obese protein,Obesity,Obesity Murine H,Obesity factor,Obesity homolog mouse,homolog of,mouse,mouse)
- Application:
- IHC
- Concentration:
- 210 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse Leptin
- Uniprot:
- P41159, P41160, P50596
- Synonyms:
- LEPD;leptin;leptin (murine obesity homolog);leptin (obesity homolog, mouse);OB;obese;obese protein;obese, mouse, homolog of;obesity factor;OBS
- Extra Details:
- This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
- Shipping Conditions:
- Blue Ice