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E-AB-70167

NFKBIB Polyclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-70167
Additional Names:
I kappa B beta,I-kappa-B-beta,IKB beta,IKBB,IkB-B,IkB-beta,IkBbeta,IkappaBbeta,NF kappa BIB,NF-kappa-B inhibitor beta,NF-kappa-BIB,Nfkbib,TR interacting protein 9,TR-intera,Thyroid receptor interacting protein 9,Thyroid receptor-interacting protein 9
Application:
IHC
Concentration:
0.66 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse IKBB Beta
Uniprot:
Q15653, Q60778, Q9JIA3
Synonyms:
I-kappa-B-beta;I(Kappa)B(beta);Ik;IKapp;ikappaBbeta;IkB;ikB-B;ikB-beta;IKBB;NF-kappa-B inhibitor beta;NF-kappa-BIB;nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta;thyroid receptor-interacting protein 9;TR-interacting protein 9;TRIP-9;TRIP9
Extra Details:
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Shipping Conditions:
Blue Ice