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E-AB-70160

CD169 Polyclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-70160
Additional Names:
CD169,CD169 antigen,DKFZp667F058,FLJ00051,FLJ00055,FLJ00073,FLJ00411,FLJ32150,Sialic acid binding Ig like lectin 1,Sialic acid binding immunoglobulin like lectin 1,Sialic acid-binding Ig-like l,dJ1009E24.1,sialic acid binding Ig-like lectin 1,sialoadhesin
Application:
IHC
Concentration:
1.4 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse CD169
Uniprot:
Q62230, Q9BZZ2
Synonyms:
CD169;SER;sheep erythrocyte receptor;sialic acid binding Ig-like lectin 1, sialoadhesin;sialic acid-binding Ig-like lectin 1;sialic acid-binding immunoglobulin-like lectin 1;sialoadhesin;Sigle;SIGLEC-1;SN
Extra Details:
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound, however, the full-length nature of this variant has not been determined.SIGLEC1 (Sialic Acid Binding Ig Like Lectin 1) is a Protein Coding gene. Diseases associated with SIGLEC1 include Proliferative Glomerulonephritis and Diffuse Cutaneous Systemic Sclerosis. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD22.
Shipping Conditions:
Blue Ice