E-AB-70139
NQO1 Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70139
- Additional Names:
- Azoreductase,Cytochrome b 5 reductase,DHQU,DIA 4,DIA4,DT diaphorase,DT-diaphorase,DTD,Diaphorase (NADH/NADPH),Diaphorase (NADH/NADPH) (cytochrome b 5 reductase),Diaphorase 4,Dioxin inducible 1,Menadione reductase,NAD(P)H ,NAD(P)H dehydrogenase [quinone] 1
- Application:
- WB
- Concentration:
- 350 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse NQO1
- Uniprot:
- P05982, P15559, Q64669
- Synonyms:
- AV001255;azoreductase;DHQU;Di;DIA4;Diaphorase (NADH/NADPH);diaphorase (NADH/NADPH) (cytochrome b-5 reductase);diaphorase 4 (NADH/NADPH);diaphorase-4;dioxin-inducible 1;DT-diaphorase;DTD;menadione reductase;NAD(P)H dehydrogenase (quinone);NAD(P)H dehydrogenase [quinone] 1;NAD(P)H dehydrogenase, quinone 1;NAD(P)H menadione oxidoreductase 1, dioxin inducible;NAD(P)H:menadione oxidoreductase;NAD(P)H:menadione oxidoreductase 1;NAD(P)H:Quinone acceptor oxidoreductase type 1;NAD(P)H:quinone oxidoreductase 1;NAD(P)H:quinone oxireductase;NM;Nmo-1;Nmo1;NMOR1;NMORI;NQ;Ox;Ox-;Ox-1;Ox1;phylloquinone reductase;QR;QR1;quinone reductase 1
- Extra Details:
- This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Shipping Conditions:
- Blue Ice