E-AB-70131
EZH2 Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70131
- Additional Names:
- Drosophila,ENX 1,ENX-1,ENX1,EZH 2,EZH1,EZH2,EZH2b,Enhancer of zeste,Enhancer of zeste 2,Enhancer of zeste homolog 2,Enhancer of zeste homolog 2 (Drosophila),Enx 1h,Enx1h,Histone-lysi,enhancer of zeste 2 polycomb repressive complex 2 subunit,homolog 2
- Application:
- WB
- Concentration:
- 0.54 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse EZH2
- Uniprot:
- Q15910, Q61188
- Synonyms:
- enhancer of zeste homolog 2;Enx-;ENX-1;ENX1;Enx1h;EZH2b;histone-lysine N-methyltransferase EZH2;KMT6;KMT6A;lysine N-methyltransferase 6;mKIAA4065;WVS;WVS2
- Extra Details:
- EZH2 (enhancer of zeste homologue 2,also known as KMT6) is a member of Polycomb group (PcG) family and encodes a histone methyl transferase that has an essential role in promoting histone H3 lysine 27 trimethylation (H3K27me3) and epigenetic gene silencing. EZH2 is important for cell proliferation and inhibition of cell differentiation,and is implicated in cancer progression. Overexpression of EZH2 is a marker of advanced and metastatic disease in many solid tumors,including prostate and breast cancer. This antibody detected EZH2 protein as a single band with a molecular weight (MW) of 91-100 kDa in multiple cell lines. The phosphorylation may result in the higher molecular weight (calculated MW as 80-86 kDa). (20935635,21367748)
- Shipping Conditions:
- Blue Ice