PGR Polyclonal Antibody

Size

£178.20

Was £198.00

SKU:: E-AB-70121
Additional Names:: NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PRA,PRB,PRGR,Progesterone receptor,Progestin receptor form A,Progestin receptor form B
Application:: IHC
Concentration:: 1.32 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:: KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor
Uniprot:: P06401, Q00175, Q63449
Synonyms:: 9930019P03Rik;BB114106;NR3;NR3C3;nuclear receptor subfamily 3 group C member 3;P;PR;PR-A;PR-B;progesterone receptor
Extra Details:: PGR,also named as NR3C3 and PR,belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.