CCL2 Polyclonal Antibody

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£178.20

Was £198.00

SKU:: E-AB-70085
Additional Names:: C-C motif chemokine 2,CCL2,Chemokine (C C motif) ligand 2,GDCF 2,GDCF-2,GDCF2,HC11,HSMCR30,JE,MCAF,MCP 1,MCP-1,MCP1,MGC9434,Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor,Monocyte chemotactic protein 1,Monocyte secretor
Application:: IHC
Concentration:: 490 ug/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:: Recombinant protein corresponding to Mouse MCP-1
Uniprot:: P10148, P13500
Synonyms:: AI323594;C-C motif chemokine 2;chemokine (C-C motif) ligand 2;GDCF-2;HC11;HSMCR30;JE;MCA;MCAF;MCP;MCP-;MCP-1;MCP1;monocyte chemoattractant protein 1;monocyte chemoattractant protein-1;monocyte chemotactic and activating factor;monocyte chemotactic protein 1;monocyte secretory protein JE;platelet-derived growth factor-inducible protein JE;Scy;SCYA2;Sig;Sigje;small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je);small inducible cytokine subfamily A (Cys-Cys), member 2;small-inducible cytokine A2;SMC-C;SMC-CF
Extra Details:: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

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