E-AB-70084
BAD Polyclonal Antibody
Size
£178.20
Was £198.00
- SKU:
- E-AB-70084
- Additional Names:
- AI325008,BAD,BBC 2,BBC2,BBC6,BCL X / BCL 2 Binding Protein,BCL X Binding Protein,Bcl 2 Antagonist of Cell Death,Bcl 2 Binding Component 6,Bcl XL/Bcl 2 Associated Death Promoter,Bcl-2-binding component 6,Bcl-2-like protein 8,Bcl-XL/Bcl-2-associated dea
- Application:
- IHC
- Concentration:
- 300 ug/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
- Immunogen:
- KLH conjugated Synthetic peptide corresponding to Mouse Bad
- Uniprot:
- O35147, Q61337, Q92934
- Synonyms:
- AI325008;Bad_v1;Bad_v2;BBC2;bcl-2 associated death agonist;bcl-2-binding component 6;bcl-2-like protein 8;BCL-X/BCL-2 binding protein;bcl-XL/Bcl-2-associated death promoter;bcl2 antagonist of cell death;Bcl2-antagonist of cell death;BCL2-antagonist of cell death protein;bcl2-associated agonist of cell death;BCL2-associated agonist of cell death, variant 1;BCL2-associated agonist of cell death, variant 2;bcl2-associated death promoter;BCL2-binding component 6;BCL2-binding protein;bcl2-L-8;BCL2L8
- Extra Details:
- The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
- Shipping Conditions:
- Blue Ice