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E-AB-70067

TNFRSF11B Polyclonal Antibody

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£178.20

Was £198.00

SKU:
E-AB-70067
Additional Names:
MGC29565,OCIF,OPG,Osteoclastogenesis inhibitory factor,Osteoprotegerin,PDB5,TNF receptor superfamily member 11b,TNFRSF 11B,TNFRSF11B,TR 1,TR1,TR11B,Tumor necrosis factor receptor superfamily member 11B
Application:
IHC
Concentration:
0.93 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol.
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Osteoprotegerin
Uniprot:
O08712, O08727
Synonyms:
O;OC;OCIF;Opg;osteoclastogenesis inhibitory factor;osteoprotegerin;TR;TR1;tumor necrosis factor receptor superfamily member 11B
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily.This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption.This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development.Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification.Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Shipping Conditions:
Blue Ice