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E-AB-68435

DSG3 Polyclonal Antibody

Size

£211.50

Was £235.00

SKU:
E-AB-68435
Additional Names:
CDHF6,DSG3,PVA
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human DSG3
Uniprot:
P32926
Synonyms:
130 kDa pemphigus vulgaris antigen;ABOLM;cadherin family member 6;CDHF6;desmoglein-3;PVA
Extra Details:
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
Shipping Conditions:
Blue Ice