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E-AB-68357

Occludin Polyclonal Antibody

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£211.50

Was £235.00

SKU:
E-AB-68357
Additional Names:
BLCPMG,OCLN,Occludin,PPP1R115,PTORCH1,occludin
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human Occludin
Uniprot:
Q16625
Synonyms:
BLCPMG;occludin;phosphatase 1, regulatory subunit 115;PPP1R115;PTORCH1
Extra Details:
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Shipping Conditions:
Blue Ice