E-AB-68310
CYP17A1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-68310
- Additional Names:
- 20 lyase,CPT7,CYP17,CYP17A1,P450C17,S17AH
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CYP17A1
- Uniprot:
- P05093
- Synonyms:
- 17-alpha-hydroxyprogesterone aldolase;CPT7;CYP17;CYPXVII;cytochrome P450 17A1;cytochrome p450 XVIIA1;cytochrome P450-C17;cytochrome P450, family 17, subfamily A, polypeptide 1;cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia;cytochrome P450c17;P450C17;S17AH;steroid 17-alpha-hydroxylase/17,20 lyase;steroid 17-alpha-monooxygenase
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
- Shipping Conditions:
- Blue Ice