E-AB-68246
DDIT3 / CHOP Polyclonal Antibody
Size
£211.50
Was £235.00
- SKU:
- E-AB-68246
- Additional Names:
- C/EBPzeta,CEBPZ,CHOP,CHOP-10,CHOP10,DDIT3,DDIT3 / CHOP,GADD153
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human DDIT3 / CHOP
- Uniprot:
- P35638
- Synonyms:
- AltDDIT3;alternative DDIT3 protein;C/EBP zeta;C/EBP-homologous protein;c/EBP-homologous protein 10;C/EBPzeta;CCAAT/enhancer-binding protein homologous protein;CEBPZ;CHOP;CHOP-10;CHOP10;DNA damage-inducible transcript 3 protein;GADD153;growth arrest and DNA damage-inducible protein GADD153
- Extra Details:
- This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
- Shipping Conditions:
- Blue Ice