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E-AB-68010

FCAR Polyclonal Antibody

Size

£285.30

Was £317.00

SKU:
E-AB-68010
Additional Names:
CD89,CTB-61M7.2,FCAR,FcalphaRI
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic Peptide of human FCAR
Uniprot:
P24071
Synonyms:
CD89;CTB-61M7.2;Fc alpha receptor;Fc fragment of IgA, receptor for;FcalphaRI;FCAR variant 14;immunoglobulin alpha Fc receptor
Extra Details:
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Shipping Conditions:
Blue Ice