SLC12A6 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-67960
Additional Names:: ACCPN,KCC3,KCC3A,KCC3B,SLC12A6
Application:: IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SLC12A6 (NP_598408.1).
Uniprot:: Q9UHW9
Synonyms:: ACCPN;electroneutral potassium-chloride cotransporter 3;K-Cl cotransporter 3;KCC3;KCC3A;KCC3B;potassium chloride cotransporter 3;potassium chloride cotransporter KCC3a-S3;potassium-chloride transporter-3a;potassium-chloride transporter-3b;solute carrier family 12 (potassium/chloride transporter), member 6;solute carrier family 12 (potassium/chloride transporters), member 6;solute carrier family 12 member 6
Extra Details:: This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.