E-AB-67665
PLA2G1B Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-67665
- Additional Names:
- PLA2,PLA2A,PLA2G1B,PPLA2
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PLA2G1B (NP_000919.1).
- Uniprot:
- P04054
- Synonyms:
- Group IB phospholipase A2;phosphatidylcholine 2-acylhydrolase 1B;phospholipase A2;phospholipase A2, group IB (pancreas);PLA2;PLA2A;PPLA2
- Extra Details:
- This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.
- Shipping Conditions:
- Blue Ice