E-AB-67662
APLP2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-67662
- Additional Names:
- APLP-2,APLP2,APPH,APPL2,CDEBP
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human APLP2 (NP_001135750.1).
- Uniprot:
- Q06481
- Synonyms:
- amyloid beta (A4) precursor-like protein 2;amyloid precursor protein homolog HSD-2;Amyloid protein homolog;amyloid-like protein 2;APLP-2;APPH;APPL2;CDEBP;CDEI box-binding protein;testicular tissue protein Li 23
- Extra Details:
- This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Shipping Conditions:
- Blue Ice