E-AB-67637
WWP1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-67637
- Additional Names:
- AIP5,Tiul1,WWP1,hSDRP1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human WWP1 (NP_008944.1).
- Uniprot:
- Q9H0M0
- Synonyms:
- AIP5;atrophin-1 interacting protein 5;Atrophin-1-interacting protein 5;HECT-type E3 ubiquitin transferase WWP1;hSDRP1;Nedd-4-like ubiquitin-protein ligase;NEDD4-like E3 ubiquitin-protein ligase WWP1;TGIF-interacting ubiquitin ligase 1;Tiul1;WW domain-containing protein 1
- Extra Details:
- WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants, however, the full length nature of these transcripts has not been defined.
- Shipping Conditions:
- Blue Ice