E-AB-67583
DOCK2 Polyclonal Antibody
Size
£285.30
Was £317.00
- SKU:
- E-AB-67583
- Additional Names:
- DOCK2,IMD40
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human DOCK2 (NP_004937.1).
- Uniprot:
- Q92608
- Synonyms:
- dedicator of cyto-kinesis 2;dedicator of cytokinesis protein 2;IMD40
- Extra Details:
- The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.
- Shipping Conditions:
- Blue Ice