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E-AB-67567

SPHK2 Polyclonal Antibody

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£285.30

Was £317.00

SKU:
E-AB-67567
Additional Names:
SK 2,SK-2,SK2,SPHK2,SPK 2,SPK-2,SPK2
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human SPHK2 (NP_001191088.1).
Uniprot:
Q9NRA0
Synonyms:
SK 2;SK-2;sphingosine kinase 2;SPK 2;SPK-2
Extra Details:
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Shipping Conditions:
Blue Ice