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E-AB-67543

HNF1A Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-67543
Additional Names:
HNF-1A,HNF1,HNF1A,IDDM20,LFB1,MODY3,TCF-1,TCF1
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human HNF1A
Uniprot:
P20823
Synonyms:
albumin proximal factor;hepatic nuclear factor 1;hepatocyte nuclear factor 1-alpha;HNF-1-alpha;HNF-1A;HNF1;HNF1alpha;HNF4A;IDDM20;interferon production regulator factor;LFB1;liver-specific transcription factor LF-B1;MODY3;TCF-1;TCF1;Transcription factor 1;transcription factor 1, hepatic;truncated hepatocyte nuclear factor 1 alpha
Extra Details:
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Shipping Conditions:
Blue Ice