Histone H3 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-67435
Additional Names:: H3.4,H3/g,H3FT,H3t,HIST1H3A,HIST3H3,Histone H3
Application:: IHC, WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human HIST3H3 (NP_003484.1).
Uniprot:: Q16695
Synonyms:: H3 histone family, member T;H3.4;H3/g;H3/t;H3FT;H3t;HIST3H3;histone 3, H3;histone cluster 3 H3;histone H3.1t;histone H3.4
Extra Details:: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.