E-AB-67421
BNP Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-67421
- Additional Names:
- BNP,NPPB
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human BNP (NP_002512.1).
- Uniprot:
- P16860
- Synonyms:
- BNP;brain natriuretic factor prohormone;brain type natriuretic peptide;gamma-brain natriuretic peptide;Iso-ANP;natriuretic peptide precursor B;natriuretic peptides B;natriuretic protein;preproBNP;proBNP
- Extra Details:
- This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
- Shipping Conditions:
- Blue Ice