E-AB-67028
TAX1BP1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-67028
- Additional Names:
- CALCOCO3,T6BP,TAX1BP1,TXBP151
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TAX1BP1 (NP_006015.4).
- Uniprot:
- Q86VP1
- Synonyms:
- CALCOCO3;T6BP;Tax1 (human T-cell leukemia virus type I) binding protein 1;tax1-binding protein 1;TRAF6-binding protein;TXBP151
- Extra Details:
- This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice