E-AB-66980
KCNA1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66980
- Additional Names:
- AEMK,EA1,HBK1,HUK1,KCNA1,KV1.1,MBK1,MK1,RBK1
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human KCNA1 (NP_000208.2).
- Uniprot:
- Q09470
- Synonyms:
- AEMK;EA1;HBK1;HUK1;KV1.1;MBK1;MK1;potassium channel, voltage gated shaker related subfamily A, member 1;potassium voltage-gated channel subfamily A member 1;potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia);RBK1;voltage-gated K(+) channel HuKI;voltage-gated potassium channel HBK1;voltage-gated potassium channel subunit Kv1.1
- Extra Details:
- This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
- Shipping Conditions:
- Blue Ice