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E-AB-66926

SNIP1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-66926
Additional Names:
PML1,PMRED,SNIP1
Application:
IHC, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human SNIP1.
Uniprot:
Q8TAD8
Synonyms:
FHA domain-containing protein SNIP1;PML1;PML1 homolog;PMRED;smad nuclear-interacting protein 1
Extra Details:
This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).
Shipping Conditions:
Blue Ice