E-AB-66907
KNG1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66907
- Additional Names:
- BDK,BK,KNG,KNG1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human KNG1 (NP_000884.1).
- Uniprot:
- P01042
- Synonyms:
- alpha-2-thiol proteinase inhibitor;BDK;BK;bradykinin;fitzgerald factor;HAE6;high molecular weight kininogen;HMWK;kininogen-1;KNG;williams-Fitzgerald-Flaujeac factor
- Extra Details:
- This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice