E-AB-66871
FREM1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66871
- Additional Names:
- BNAR,C9orf143,C9orf145,C9orf154,FREM1,MOTA,TILRR,TRIGNO2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human FREM1 (NP_659403.4).
- Uniprot:
- Q5H8C1
- Synonyms:
- BNAR;C9orf143;C9orf145;C9orf154;extracellular matrix protein QBRICK;FRAS1-related extracellular matrix protein 1;MOTA;Protein QBRICK;TILRR;TRIGNO2
- Extra Details:
- This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.
- Shipping Conditions:
- Blue Ice