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E-AB-66818

STAR Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-66818
Additional Names:
STAR,STAR ,STARD1
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human STAR
Uniprot:
P49675
Synonyms:
cholesterol trafficker;mitochondrial steroid acute regulatory protein;StAR related lipid transfer (START) domain containing 1;STARD1;START domain containing 1;START domain-containing protein 1;steroid acute regulatory protein;steroidogenic acute regulator;steroidogenic acute regulatory protein, mitochondrial;testis secretory sperm-binding protein Li 241mP
Extra Details:
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
Shipping Conditions:
Blue Ice