E-AB-66670
RAPGEF1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66670
- Additional Names:
- C3G,GRF2,RAPGEF1
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human RAPGEF1 (NP_941372.1).
- Uniprot:
- Q13905
- Synonyms:
- C3G;CRK SH3-binding GNRP;GRF2;Guanine nucleotide-releasing factor 2;guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene);Protein C3G;Rap guanine nucleotide exchange factor (GEF) 1;rap guanine nucleotide exchange factor 1
- Extra Details:
- This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
- Shipping Conditions:
- Blue Ice