E-AB-66584
GCAT Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66584
- Additional Names:
- GCAT,KBL
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human GCAT (NP_055106.1).
- Uniprot:
- O75600
- Synonyms:
- 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial;2-amino-3-ketobutyrate-CoA ligase;AKB ligase;aminoacetone synthase;glycine acetyltransferase;KBL
- Extra Details:
- The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.
- Shipping Conditions:
- Blue Ice