SIRT4 Polyclonal Antibody

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£195.30

Was £217.00

SKU:: E-AB-66582
Additional Names:: SIR2L4,SIRT4,sirtuin 4
Application:: IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SIRT4 (NP_036372.1).
Uniprot:: Q9Y6E7
Synonyms:: NAD-dependent ADP-ribosyltransferase sirtuin-4;NAD-dependent protein deacetylase sirtuin-4;NAD-dependent protein lipoamidase sirtuin-4, mitochondrial;regulatory protein SIR2 homolog 4;sir2-like 4;SIR2-like protein 4;SIR2L4;sirtuin type 4
Extra Details:: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.