E-AB-66498
ACACA Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-66498
- Additional Names:
- ACAC,ACACA,ACACAD,ACC,ACC1,ACCA
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human ACACA
- Uniprot:
- Q13085
- Synonyms:
- ACAC;ACACAD;ACC;ACC-alpha;ACC1;ACCA;acetyl-CoA carboxylase 1;acetyl-Coenzyme A carboxylase alpha
- Extra Details:
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice